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CODESYS comes with built-in support for Ironpython. The Ironpython scripts are running inside of the CODESYS IDE, and can be used to automate huge parts of the system. That virtually everything within CODESYS can be automated this way, and that CODESYS can even be started headless, running a python script, makes the system really mighty.
There are many use cases you can think of:
... will come...
cforge heavily uses the scripting API to automate some workflows for developers.